Mouse IgG-SAP

Catalog #IT-18

   
   
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a chemical conjugate of pre-immune mouse IgG antibody
and the ribosome-inactivating protein, saporin

serves as a control for mouse IgG-containing immunolesioning agents

Mouse IgG-SAP serves as a control for the targeted toxins that use a mouse monoclonal: 192-IgG-SAP, OX7-SAP, Anti-DBH-SAP, ME20.4-SAP, Anti-SERT-SAP, Anti-CD25-SAP human, Mac-1-SAP rat, Anti-CD22-SAP, Anti-6 His-ZAP, Anti-GFP-ZAP, Anti-Basigin2-SAP, Anti-V5-ZAP, and Anti-FLAG (M5)-ZAP. This control molecule is the same molecular weight, consists of similar, comparable materials (saporin and a mouse IgG) and is synthesized with the same protocols as the targeted toxins. The difference is the cell-specific targeting agents are replaced with "blanks," antibodies or peptides that have no specificity, and no ability to target cells.

Effective Tool

  • The perfect control molecule for targeted immunotoxins
  • There's no mixing of reagents; use it "as is" out of the vial
  • No complicated calculations; use the same amount as the targeted toxin
  • Ready to use: it comes sterile-filtered in phosphate-buffered saline
  • It has the activity of non-targeted saporin, that is, almost none
Mouse IgG-SAP

news articleCheck out these articles in Targeting Trends for more information:


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