a chemical conjugate between a non-targeted peptide
and the ribosome-inactivating protein, saporin

(molecular weight 32 kDa)

This molecule is the perfect control for use with peptide conjugates such as: SSP-SAP, Dermorphin-SAP, CRF-SAP, Orexin-SAP, NPY-SAP, CCK-SAP, and Galanin-SAP. The sequence of the non-targeted peptide of Blank-SAP is an 11-amino acid, randomly mixed version of the sequence of melanocyte-stimulating hormone, with amino acid residues that are typical of peptides that bind to G-protein-coupled receptors. Examination of the peptide sequence using NCBI/BLAST reveals no homologous sequences. Thus, Blank-SAP can be used as control for any non-specific effects of the toxin and provides a definitive baseline for determining the effects of a targeted peptide conjugate.

Effective Tool