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Saporin
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Saporin is a ribosome-inactivating protein, molecular weight 30kD, from seeds of the plant Saponaria officinalis.
Effective Tool
Sample Protocol
For most targeted toxins, there are control conjugates available (see list); these are the most accurate controls to use. For a few products, saporin is used as control. Calculate amount of saporin needed on a molar basis. For example, for FGF-SAP (Cat. #IT-38) has an average mol. wt. of 63 kDa, and 71% of that is saporin (approximately 1.5 molecules of saporin per molecule of cytokine). For injections of 5 µg of immunotoxin, an appropriate control quantity would be 3.6 µg.
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