a chemical conjugate of affinity-purified goat anti-rabbit IgG
and the ribosome-inactivating protein, saporin
Rab-ZAP uses your primary rabbit affinity-purified polyclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified goat anti-rabbit IgG) to "piggyback" onto YOUR rabbit primary antibody. Rab-ZAP can be utilized for screening rabbit IgG antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.
Fab-ZAP rabbit (Cat. #IT-57) is also available and uses a monovalent antibody conjugate to target your rabbit polyclonal IgG.
Elimination of Specific Cell Type
- Cells that internalize your rabbit affinity-purified polyclonal antibody will be eliminated.
- Potency may vary according to the specificity and affinity of YOUR antibody to ITS receptor.
- Second immunotoxins are most effective in determining specificity of your polyclonal antibody and suitability for conjugation as a primary immunotoxin.
- ATS recommends that you order a custom conjugation of your antibody to saporin when the in vitro results confirm the desired specificity.
Check out these articles in Targeting Trends for more information:
Please select the button below for Cat. #IT-05 Pricing in your currency. The kit includes the following controls: Goat IgG-SAP, Cat. #IT-19;
This product is available individually and as a kit (Cat. #KIT-05).
The kit includes the following controls: Goat IgG-SAP, Cat. #IT-19;
You may also be interested in these products for Rab-ZAP, Cat. #IT-05.
Controls: Goat IgG-SAP, Cat. #IT-19;
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