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Goat-ZAP Catalog #IT-36 |
Goat-ZAP uses your goat primary antibody to target and eliminate cells. Upon binding to a goat IgG that recognizes an extracellular domain of a cell surface antigen, Goat-ZAP will be taken inside the cell by antibody-mediated internalization. The entrance of saporin into the cell will result in protein synthesis inhibition and eventual cell death after 2-4 days. This reagent can be utilized for screening goat IgG antibodies for internalization and/or their suitability to make potent immunotoxins.
Elimination of Specific Cell Type
Protocols: Preparing for a Cytotoxicity Assay; Preparing Test Samples
Check out these articles in Targeting Trends for more information:Please select the button below for Cat. #IT-36 Pricing in your currency.
This product is available individually and as a kit. The kit includes the following controls: IT-35
You may also be interested in these products for Goat-ZAP ^, Cat. #IT-36.
Controls: Rabbit IgG-SAP, Cat. #IT-35;
Related Products: Custom Conjugates;
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