a chemical conjugate of affinity-purified goat anti-human IgM
and the ribosome-inactivating protein, saporin

Hug-M-ZAP is a "second" immunotoxin that relies on your antibody for cytotoxicity to target cells.

Elimination of Specific Cell Type

• Cells that internalize your human monoclonal IgM antibody will be eliminated.
• Potency may vary according to the specificity and affinity of YOUR antibody to ITS receptor.
• Second immunotoxins are most effective in determining specificity of your monoclonal antibody and suitability for conjugation as a primary immunotoxin.
• ATS recommends that you order a custom conjugation of your antibody to saporin when the in vitro results confirm the desired specificity

Protocols: Preparing for a Cytotoxicity Assay; Preparing Test Samples