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Acetylated LDL-SAP

a chemical conjugate of acetylated human low density lipoprotein
and the ribosome-inactivating protein, saporin

Acetylated-LDL-Saporin (acLDL-SAP) has been used effectively to eliminate microglia from primary cultures of rat hippocampal neurons, while having no deleterious effect on neurons or astroglia. After 24 hours exposure, 3 µg/ml of acetylated-LDL-SAP selectively kills more than 90% of microglia cells.

Elimination of Specific Cell Type

Effective Tool to Study Disease States

news article

Check out this article in Targeting Trends for more information.

Jul-Aug-Sep 2004 - Microglia in your neuronal culture behaving badly? Eliminate them with AcLDL-SAP
Standard Pricing
IT-08-25 25 micrograms
$110
IT-08-100 100 micrograms
$400
IT-08-250 250 micrograms
$945
Kit Pricing
includes Saporin for control
KIT-08-25 25 micrograms
$145
KIT-08-100 100 micrograms
$535
KIT-08-250 250 micrograms
$1265

References

Data Sheet

Summary

Controls: Saporin (Cat. #PR-01)

 

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