Dermorphin-SAP / MOR-SAP

Catalog #IT-12

   
   
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a chemical conjugate of dermorphin and the ribosome-inactivating protein, saporin

targets cells expressing mu-opioid receptor (MOR)

Dermorphin-SAP (MOR-SAP) targets and eliminates cells expressing the mu opioid receptor (MOR). MOR-expressing neurons have long been considered some of the most important cells in the nervous systems because of their participation in pain, pain control, addiction, gastrointestinal motility, and mast cell function, among others. This specific cytotoxin provides new methods for understanding these neurons and how they work. MOR-SAP is not suitable for retrograde transport.

Elimination of Specific Cell Type

  • Mu opioid receptor-expressing cells are eliminated with this reagent
  • All other cells are left untouched.
  • Not suitable for retrograde transport.

Effective Tool to Study Behavior

Permanent and selective removal of MOR-expressing neurons makes an important animal model for the study of the following:

  • Pain
  • Pain control
  • Addiction
  • Gastrointestinal motility
  • Mast cell function
MOR-SAP

news articleCheck out these articles in Targeting Trends for more information:


Please select the button below for Cat. #IT-12 Pricing in your currency.
This product is available individually and as a kit (Cat. #KIT-12).

The kit includes the following controls: Saporin, Cat. #PR-01Blank-SAP, Cat. #IT-21

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References     Data Sheet     

You may also be interested in these products for Dermorphin-SAP / MOR-SAP ^, Cat. #IT-12.

Controls: Saporin, Cat. #PR-01Blank-SAP, Cat. #IT-21

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