Anti-CD25-SAP mouse

Catalog #IT-29

   
   
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a chemical conjugate of a monoclonal antibody to mouse CD25 (Tac, IL-2 receptor, Cat #AB-19)
and the ribosome-inactivating protein, saporin

targets cells expressing mouse CD25

The CD25 monoclonal antibody inhibits the proliferation of interleukin-2 (IL-2)-dependent human continuous T-cell lines. It blocks the human T-cell receptor for IL-2 by binding to the alpha-chain of the IL-2 receptor. Anti-CD25-SAP specifically eliminates cells expressing mouse CD25 and is potently cytotoxic to mouse activated T-cells. Anti-CD25 immunotoxins have been shown to remove activated T lymphocytes in culture, and can be used to understand the role of this population in its various processes in the immune system. It has also been suggested for clinical use in the treatment of T-cell leukemias and lymphomas.

To eliminate CD25-expressing cells in human, use Anti-CD25-SAP human (Cat. #IT-24).

Elimination of Specific Cell Type

  • Specifically eliminates cells that express the murine interleukin-2 (IL-2) receptor.
  • All other cells are left untouched.

Effective Tool

  • Anti-CD25 immunotoxins have been shown to remove activated T lymphocytes in culture, and can be used to understand the role of this population in its various processes in the immune system.

news articleCheck out these articles in Targeting Trends for more information:


Please select the button below for Cat. #IT-29 Pricing in your currency.
This product is available individually and as a kit (Cat. #KIT-29).

The kit includes the following controls: Saporin, Cat. #PR-01CD25 Rat Monoclonal, Cat. #AB-19Rat IgG-SAP, Cat. #IT-17

USD     EURO     GBP

References     Data Sheet

You may also be interested in these products for Anti-CD25-SAP mouse, Cat. #IT-29.

Controls: Saporin, Cat. #PR-01CD25 Rat Monoclonal, Cat. #AB-19Rat IgG-SAP, Cat. #IT-17

Related Products: Anti-CD25-SAP human, Cat. #IT-24CD25 Mouse Monoclonal, Cat. #AB-18

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