a chemical conjugate of native oxytocin peptide and the ribosome-inactivating protein, saporin
targets cells expressing oxytocin receptor

Oxytocin is a nine amino acid peptide with a structure similar to vasopressin, and is a hormone released by the posterior pituitary. Peripheral activity of oxytocin is linked primarily to lactation and labor-related uterine contractions. Within the brain, oxytocin receptor-positive neurons have been studied with regard to their sensitivity to leptin and involvement in satiety.

Elimination of Specific Cell Type

• Oxytocin-receptor positive cells are eliminated with this reagent
• All other cells are left untouched.