Dermorphin-SAP (Cat. #IT-12) Kills MOR-Positive Cells - continued on page 6

A Tribute to Thomas J. Walsh, Ph.D.

Going to Work is Like a Walk in the Park

Featured Neuroscience Antibodies: Nerve Growth Factor (p75) Receptor

• NGFR (Cat. #AB-N01) rabbit polyclonal
• NGFR (Cat. #AB-N02) rat monoclonal IgG1
• NGFR (Cat. #AB-N07) mouse monoclonal ME20.4 IgG

• Zheng, F. and Khanna, S. (2001) Selective destruction of medial septal cholinergic neurons attenuates pyramidal cell suppression, but not excitation in dorsal hippocampus field CA1 induced by subcutaneous injection of formalin. Neurosci 103(4):985-998. (192-IgG-SAP, Cat. #IT-01)
• Hartlage-Rubsamen, M., Schliebs, R. (2001) Sequential upregulation of cell adhesion molecules in degenerating rat basal forebrain cholinergic neurons and in phagocytotic microglial cells. Brain Res 897(1-2):20-26. (192-IgG-SAP, Cat. #IT-01)
• Ritter, S., Bugarith, K., Dinh, T.T. (2001) Immunotoxic destruction of distinct catecholamine subgroups produces selective impairment of glucoregulatory responses and neuronal activation. J Comp Neurol 432(2):197-216. (Anti-DBH-SAP, Cat. #IT-03)
• Paqueron, X., Li, X., Eisenach, J.C.(2001) p75-expressing elements are necessary for anti-allodynic effects of spinal clonidine and neostigmine. Neurosci 102(3):681-686. (192-IgG-SAP, Cat. #IT-01)
• Wiley, R.G. (2000) Neuropeptide-toxin conjugates in pain research and treatment. (Review) Reg Anesth Pain Med 25(5):546-548. (SP-SAP, Cat. #IT-07)

• Hartlage-Rubsamen, M., Schliebs, R. (2001) Rat basal forebrain cholinergic lesion affects neuronal nitric oxide synthase activity in hippocampal and neocortical target regions. Brain Res 889(1-2):155-164. (192-IgG-SAP, Cat. #IT-01)
• Perry, T., Hodges, H., Gray, J.A. (2001) Behavioural, histological and immunocytochemical consequences following 192 IgG-Saporin immunolesions of the basal forebrain cholinergic system. Brain Res Bull 54(1):29-48. (192-IgG-SAP, Cat. #IT-01)
• Ferencz, I., Leanza, G., Nonobashvili, A., Kokaia, Z., Kokaia, M., Lindvall, O. (2001) Septal cholinergic neurons suppress seizure development in hippocampal kindling in rats: comparison with noradrenergic neurons. Neurosci 102(4): 819-832. (192-IgG-SAP, Cat. #IT-01)
• Wiley, R.G. (2001) Toxin-induced death of neurotrophin-sensitive neurons. (Review) Meth Mol Biol 169(1-2):217-222. (192-IgG-SAP, Cat. #IT-01)
• Gu, Z., Wortwein, G., Yu, J., Perez-Polo, J.R. (2000) Model for aging in the basal forebrain cholinergic system. (Review) Antiox Redox Signal 2(3):437-447. (192-IgG-SAP, Cat. #IT-01)

• What are the options for delivery of targeted toxins?
• When injecting directly into tissue, are there any special techniques that should be used?
• What sort of special care should be given to the animal after administration of the targeted toxin?

Dermorphin-SAP (Cat. #IT-12) Kills MOR-Positive Cells - continued from page 1

Targeting Ticklers (Jokes)

Targeting Teaser Winners from last issue

•  Saporin (Cat. #PR-01): a ribosome-inactivating protein

Targeting Teaser (Jumble)