Subplate Neurons and Functional Maturation of Thalamocortical Synapses
(continued on page 6)

Contributed by Dr. Patrick O. Kanold, Dept Neurobiology, Harvard Medical School, Boston, MA 02115. Dr. Kanold summarizes his work with ME20.4-SAP. A complete report was published in Science 301:521-525.

Product information related to cover article: ME20.4-SAP (Cat. #IT-15)

Surfboards for Spinal Cords, September 27 in Ocean Beach, CA

ATS Receives $2.4 M Award for SP-SAP Drug Development (see Press Release)

• Wiley RG, Lappi DA (2003) Targeted toxins in pain. Adv Drug Deliv Rev 55(8):1043-1054.
• Gadd CA, Murtra P, De Felipe C, Hunt SP (2003) Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse. J Neurosci 23(23):8271-8280. (SP-SAP, Cat. #IT-07)
• Kanold PO, Kara P, Reid RC, Shatz CJ (2003) Role of subplate neurons in functional maturation of visual cortical columns. Science 301(5632):521-525. (ME20.4-SAP, Cat. #IT-15)
• Ricceri L (2003) Behavioral patterns under cholinergic control during development: lessons learned from the selective immunotoxin 192 IgG saporin. Neurosci Biobehav Rev 27(4):377-384. (192-IgG-SAP, Cat. #IT-01)
• Levita L, Mania I, Rainnie DG (2003) Subtypes of substance P receptor immunoreactive interneurons in the rat basolateral amygdala. Brain Res 981(1-2):41-51. (SP-SAP, Cat. #IT-07)

Recent Scientific References

• Lehmann O, Grottick AJ, Cassel JC, Higgins GA (2003) A double dissociation between serial reaction time and radial maze performance in rats subjected to 192 IgG-saporin lesions of the nucleus basalis and/or the septal region. Eur J Neurosci 18(3):651-666. (192-IgG-SAP, Cat. #IT-01)
• Pappas BA, Sherren N (2003) Neonatal 192 IgG-saporin lesion of forebrain cholinergic neurons: focus on the life span? Neurosci Biobehav Rev 27(4):365-376. (192-IgG-SAP, Cat. #IT-01)
• Cadiacio CL, Milner TA, Gallagher M, Pierce JP (2003) Hilar neuropeptide Y interneuron loss in the aged rat hippocampal formation. Exp Neurol 183(1):147-158. (192-IgG-SAP, Cat. #IT-01)
• Kirby BP, Rawlins JN (2003) The role of the septo-hippocampal cholinergic projection in T-maze rewarded alternation. Behav Brain Res 143(1):41-48. (192-IgG-SAP, Cat. #IT-01)
• Conner JM, Culberson A, Packowski C, Chiba AA, Tuszynski MH (2003) Lesions of the basal forebrain cholinergic system impair task acquisition and abolish cortical plasticity associated with motor skill learning. Neuron 38(5):819-829. (192-IgG-SAP, Cat. #IT-01)
• Gardell LR, Vanderah TW, Gardell SE, Wang R, Ossipov MH, Lai J, Porreca F (2003) Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation. J Neurosci 23(23):8370-8379. (Dermorphin-SAP, Cat. #IT-12)

Targeting Tests: CCK-SAP in Binding Studies

Our thanks to Drs. Frank Porecca, Victory Hruby and Josephine Lai, Department of Pharmacology, The University of Arizona Health Sciences Center for sharing the results of their studies.

Product information related to article: CCK-SAP (Cat. #IT-31)

Subplate Neurons and Functional Maturation of Thalamocortical Synapses
(continued from page 1)

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