Selective lesion of basal forebrain cholinergic neurons in mice with the mu p75-saporin immunotoxin: Neuroanatomy and behavior
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Contributed by Pierre-Henri Moreau, Brigitte Cosquer, Hélène Jeltsch, Jean-Christophe Cassel, Chantal Mathis
Laboratoire d’Imagerie et de Neurosciences Cognitives, UMR7191 CNRS, Equipe de Neurobiologie Cognitive et Comportementale, Université Louis Pasteur, IFR 37 de Neurosciences, GDR 2905 CNRS, 12 rue Goethe, 67000 Strasbourg, France

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Recent Scientific References

• Moreau PH, Cosquer B, Jeltsch H, Cassel JC, Mathis C (2008) Neuroanatomical and behavioral effects of a novel version of the cholinergic immunotoxin mu p75-saporin in mice. Hippocampus [Epub Feb 27]. (Cat. #IT-16; Cat. #IT-01)
• Pijpers A, Winkelman BH, Bronsing R, Ruigrok TJ (2008) Selective impairment of the cerebellar C1 module involved in rat hind limb control reduces step-dependent modulation of cutaneous reflexes. J Neurosci 28:2179-2189. (Cat. #IT-14)
• Aztiria E, Cataudella T, Spampinato S, Leanza G (2008) Septal grafts restore cognitive abilities and amyloid precursor protein metabolism. Neurobiol Aging [Epub Feb 5]. (Cat. #IT-01)
• Rostron CL, Farquhar MJ, Latimer MP, Winn P (2008) The pedunculopontine tegmental nucleus and the nucleus basalis magnocellularis: do both have a role in sustained attention? BMC Neurosci 9:16. (Cat. #IT-01)
• Kline RHt, Wiley RG (2008) Spinal mu-opioid receptor-expressing dorsal horn neurons: role in nociception and morphine antinociception. J Neurosci 28:904-913. (Cat. #IT-12; Cat. #IT-21; Cat. #PR-01)
• Kalinchuk AV, Porkka-Heiskanen T, McCarley RW (2006) Basal forebrain and saporin cholinergic lesions: the devil dwells in delivery details. Sleep 29:1385-1387; discussion 1387-1389. (Cat. #IT-01)

Recent Scientific References

• Newman LA, McGaughy J (2008) Cholinergic Deafferentation of Prefrontal Cortex Increases Sensitivity to Cross-Modal Distractors during a Sustained Attention Task. J Neurosci 28:2642-2650. (Cat. #IT-01)
• Kaur S, Junek A, Black MA, Semba K (2008) Effects of ibotenate and 192IgG-saporin lesions of the nucleus basalis magnocellularis/substantia innominata on spontaneous sleep and wake states and on recovery sleep after sleep deprivation in rats. J Neurosci 28:491-504. (Cat. #IT-01)
• Khan IM, Wart CV, Singletary EA, Stanislaus S, Deerinck T, Yaksh TL, Printz MP (2008) Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists. Neuropharmacology 54:269-279. (Cat. #IT-07; Cat. #PR-01)
• Domico LM, Cooper KR, Bernard LP, Zeevalk GD (2007) Reactive oxygen species generation by the ethylene-bis-dithiocarbamate (EBDC) fungicide mancozeb and its contribution to neuronal toxicity in mesencephalic cells. Neurotoxicology 28:1079-1091. (Cat. #IT-33)
• Li A, Emond L, Nattie E (2008) Brainstem catecholaminergic neurons modulate both respiratory and cardiovascular function. Adv Exp Med Biol 605:371-376. (Cat. #IT-03; Cat. #IT-18)

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Selective lesion of BFCN with mu p75-SAP
(continued from page 1)

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